Russia's military invasion of Ukraine has not only caused one of the world's most tragic humanitarian crises but resulted in economic devastation that will influence territories far beyond Ukraine's borders. Main project activity is to create a friendly economic environment for woman entrepreneurs and innovators from Ukraine but also from others countries in a similar situation. It includes establishing instrument: transnational fund/mechanism/network. Project is territorially oriented at all BS regions. The different economic environment in partnership gives possibility to choose preferred country for each start-up referred to regional specializations. We plan to settle single eco-system for viable or innovative start-up’s from Ukraine. BS regions will benefit from boosting entrepreneurship and competitive (knowledge-based) transnational economic relations. All EU members and their economies will benefit from professional activation of vulnerable groups of refugees but what is the most relevant, war immigrants will be supported with professional, long term business oriented help. It will prevent a number of social issues and immigration- related problems. It is worth to mentioned that one of the aspects of recovering from a war or catastrophic trauma in its last phase is taking up professional activity. Rebuilding life anew, is greatly helped by any professional and economic activity. It influences not only economy but also mental wellbeing of populations.